Aspergillus niger

By Targets:	Antibiotic (2) Apoptosis (1) Bacterial (3) Endogenous Metabolite (2) Fungal (3) Reactive Oxygen Species (1)
By Research Areas:	Cancer (4) Infection (5) Metabolic Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-135849

Catalase, Aspergillus niger 1 Publications Verification	Reactive Oxygen Species	Cancer
Catalase, Aspergillus niger is a key enzyme in the metabolism of H₂O₂ and reactive oxygen species (ROS), and its expression and localization is markedly altered in tumors . Free oxygen radical scavenger.

HY-P2857

Amyloglucosidase, Aspergillus niger Amyloglucosidase; 1,4-α-D-Glucan glucohydrolase; Exo-1,4-α-glucosidase	Others	Metabolic Disease
Amyloglucosidase, Aspergillus niger is an enzyme derived from many sources including plants, animals and microorganisms, can be use for industrial production. Amyloglucosidase can be widely used for starch saccharification, brewing and distilling industry .

HY-E70222

Phytase, from Aspergillus niger	Others	Others
Phytase, from Aspergillus niger degrades phytic acid into inositol and phosphate. Phytase, from Aspergillus niger phytase treatment can minimize the anti-nutritional effect of phytic acid .

HY-P2871

α-Galactosidase, Aspergillus niger EC 3.2.1.22	Endogenous Metabolite	Others
α-Galactosidase, Aspergillus niger (EC 3.2.1.22), that is, α-galactosidase, is a glycoside hydrolase that widely exists in animals, plants and microorganisms, and is often used in biochemical research. α-Galactosidase catalyzes the hydrolysis of α-1,6-linked terminal galactose residues, including galactooligosaccharides, galactomannans, and galactolipids. Catalyzes many catabolic processes including cleavage of glycoproteins, glycolipids and polysaccharides .

HY-N3687

Dasycarpol	Others	Cancer
Dasycarpol (compound 2) is a product of microbial transformation of fraxinellone by Aspergillus niger (AS 3.421). Dasycarpol shows moderate cytotoxicity against A549 cells ,with the IC₅₀ of 20 ug/mL .

HY-P2124

Cyclo(L-Trp-L-Trp)	Antibiotic Bacterial	Infection
Cyclo(L-Trp-L-Trp) is an antibiotic, and shows antimicrobial activity. Cyclo(L-Trp-L-Trp) can inhibit A. baumannii, as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae, Aspergillus niger, Staphylococcus aureus. Cyclo(L-Trp-L-Trp) can be used in microbial infection research .

HY-126386

Pectinase, aspergillus niger EC 3.2.1.15	Others	Others
Pectinase (EC 3.2.1.15) is a mixed enzymes that hydrolyze pectic substances, it mostly presents in microorganisms and higher plants. Pectinase is involved in the metabolism of the cell wall as well as in the growth of the cell, senescence, ripening of fruits, pathogenesis and abscission process .

HY-E70105

α-Xylosidase AxlA	Others	Others
α-Xylosidase (AxlA) belongs to the GH31 family of glycoside hydrolases and catalyzes the hydrolysis of an α1,6-linked xyloside. α-Xylosidase can effectively release terminal xylose from xyloglucan, a major plant hemicellulose .

HY-109706

(Rac)-CPI-098	Bacterial Fungal	Infection
(Rac)-CPI-098 shows antibacterial activity. (Rac)-CPI-098 exhibits superior anti-fungal activity against Monascus ruber, better activity against Aspergillus fumigates, good activity against Aspergillus niger and Aspergillus parasites and moderate activity against Candida albicans .

HY-N6783

Oligomycin C	Fungal Antibiotic	Infection
Oligomycin C is a macrolide antibiotic produced by Streptomyces strains. Oligomycin C exhibits a strong activity against Aspergillus niger, Alternaria alternata, Botrytis cinerea and Phytophthora capsici but no activity toward bacteria .

HY-E70107

Cellobiohydrolase I Cbh1	Others	Others
Cellobiohydrolase I (Cbh1) belongs to glycoside hydrolase family 7 (GH7) that catalyzes the processive hydrolysis of cellulose into cellobiose .

HY-P2569

Malformin A1	Apoptosis	Cancer
Malformin A1, a cyclic pentapeptide isolated from Aspergillus niger, possess a range of bioactive properties including antibacterial activity. Malformin A1 shows potent cytotoxic activities on human colorectal cancer cells. Malformin A1 induces apoptosis by activating PARP, caspase 3, -7, and -9 .

HY-P2902

Glucose oxidase 2 Publications Verification	Endogenous Metabolite	Cancer
Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O₂) to produce hydrogen peroxide (H₂O₂) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation .

HY-136153

Amphotericin X1	Fungal	Infection
Amphotericin X1 is an 13-O-methyl derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, C.parapsilosis 937A, Cryptococcus neoformans 451, Aspergillus niger 57A and *A.fumigatus* with MIC values of 1 μg/mL, 8 μg/mL, 1 μg/mL, 2 μg/mL and 2 μg/mL, respectively .

HY-N2544

Dehydroglaucine

Bacterial Infection

Dehydroglaucine is a potent antimicrobial alkaloid .

Dehydroglaucine	Bacterial	Infection
Dehydroglaucine is a potent antimicrobial alkaloid .

Cat. No.	Product Name	Type

HY-P2902

Glucose oxidase 2 Publications Verification	Biochemical Assay Reagents
Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O₂) to produce hydrogen peroxide (H₂O₂) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation .

HY-P2996

NAD(P)H-Nitrate reductase	Biochemical Assay Reagents
NAD(P)H-Nitrate reductase is isolated from Aspergillus niger that catalyses the reduction of nitrate to nitrite via a two-electron transfer. In plants, the electron donor for Nitrate reductase is NADPH is NADH:Nitrate reductase and a bispecific NAD(P)H: Nitrate reductase .

Cat. No.	Product Name	Target	Research Area

HY-P2124

Cyclo(L-Trp-L-Trp)	Antibiotic Bacterial	Infection
Cyclo(L-Trp-L-Trp) is an antibiotic, and shows antimicrobial activity. Cyclo(L-Trp-L-Trp) can inhibit A. baumannii, as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae, Aspergillus niger, Staphylococcus aureus. Cyclo(L-Trp-L-Trp) can be used in microbial infection research .

HY-P2996

NAD(P)H-Nitrate reductase	Peptides	Others
NAD(P)H-Nitrate reductase is isolated from Aspergillus niger that catalyses the reduction of nitrate to nitrite via a two-electron transfer. In plants, the electron donor for Nitrate reductase is NADPH is NADH:Nitrate reductase and a bispecific NAD(P)H: Nitrate reductase .

HY-P2569

Malformin A1	Apoptosis	Cancer
Malformin A1, a cyclic pentapeptide isolated from Aspergillus niger, possess a range of bioactive properties including antibacterial activity. Malformin A1 shows potent cytotoxic activities on human colorectal cancer cells. Malformin A1 induces apoptosis by activating PARP, caspase 3, -7, and -9 .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P2857

Amyloglucosidase, Aspergillus niger Amyloglucosidase; 1,4-α-D-Glucan glucohydrolase; Exo-1,4-α-glucosidase	Structural Classification Natural Products Microorganisms Classification of Application Fields Animals Source classification Metabolic Disease Disease Research Fields	Others
Amyloglucosidase, Aspergillus niger is an enzyme derived from many sources including plants, animals and microorganisms, can be use for industrial production. Amyloglucosidase can be widely used for starch saccharification, brewing and distilling industry .

HY-N3687

Dasycarpol	Structural Classification Natural Products Microorganisms Source classification	Others
Dasycarpol (compound 2) is a product of microbial transformation of fraxinellone by Aspergillus niger (AS 3.421). Dasycarpol shows moderate cytotoxicity against A549 cells ,with the IC₅₀ of 20 ug/mL .

HY-N6783

Oligomycin C	Infection Structural Classification Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Disease Research Fields	Fungal Antibiotic
Oligomycin C is a macrolide antibiotic produced by Streptomyces strains. Oligomycin C exhibits a strong activity against Aspergillus niger, Alternaria alternata, Botrytis cinerea and Phytophthora capsici but no activity toward bacteria .

HY-P2569

Malformin A1	Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Apoptosis
Malformin A1, a cyclic pentapeptide isolated from Aspergillus niger, possess a range of bioactive properties including antibacterial activity. Malformin A1 shows potent cytotoxic activities on human colorectal cancer cells. Malformin A1 induces apoptosis by activating PARP, caspase 3, -7, and -9 .

HY-N2544

Dehydroglaucine	Infection Alkaloids Classification of Application Fields Source classification Magnoliaceae Liriodendron tulipifera L. Quinoline Alkaloids Plants Disease Research Fields	Bacterial
Dehydroglaucine is a potent antimicrobial alkaloid .

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